Starna DNACON is a Certified Reference Material designed for quality control and assurance of nucleic acid purity measurements based on the 260/280 nm absorbance ratio. The 260/280 ratio is a standard indicator of nucleic acid purity, where pure DNA and RNA solutions have ratios of ≥ 1.8 and ≥ 2.0 respectively.
This reference consists of a synthetic solution whose spectral characteristics closely mimic those of DNA, sealed permanently in a far-UV quartz cell. It provides a stable, reliable, and NIST-traceable standard that replicates actual DNA sample absorbance, enabling direct validation of the measurement process. The 280 nm absorbance is measured on a steep spectral slope, meaning small wavelength variations (±1 nm) significantly affect the ratio, emphasizing the need for precise instrument qualification.
Starna DNACON is a Certified Reference Material designed for quality control and assurance of nucleic acid purity measurements based on the 260/280 nm absorbance ratio. The 260/280 ratio is a standard indicator of nucleic acid purity, where pure DNA and RNA solutions have ratios of ≥ 1.8 and ≥ 2.0 respectively.
This reference consists of a synthetic solution whose spectral characteristics closely mimic those of DNA, sealed permanently in a far-UV quartz cell. It provides a stable, reliable, and NIST-traceable standard that replicates actual DNA sample absorbance, enabling direct validation of the measurement process. The 280 nm absorbance is measured on a steep spectral slope, meaning small wavelength variations (±1 nm) significantly affect the ratio, emphasizing the need for precise instrument qualification.
